St Vincent’s Biobank was established in 2010 to provide St Vincent’s Hospital Darlinghurst campus researchers with infrastructure to manage valuable and high quality biological tissues and samples in support of biomedical research and clinical trials. The facility was purpose built to address many of the workplace health and safety issues with handling cryogenic fluids, pressurised gases and biospecimens which may be biologically hazardous eg. oncogenic, infectious microorganisms as well as genetically modified organisms (GMOs). The facility complies with a range of legislative and best practice standards.
St Vincent’s Centre for Applied Medical Research (AMR) is the lead Partner for the St Vincent’s Research Precinct for the provision of cryogenics infrastructure and is responsible for user training and maintenance of the infrastructure.
St Vincent’s Hospital Sydney endorsed a policy that recognizes the contribution that is made by those who donate human tissues and samples for medical research. This policy observes the fundamental ethical principle of respect of the donor, including the provision of fully informed consent, professional collection of samples and secure storage of materials and to maintain confidentiality and privacy.
While many biobanks are traditionally focussed on solid tumour and cancer tissue, the St Vincent’s repository also hold extensive collections of blood, tissue and derivative (plasma, serum, DNA, nucleic acid extracts, genetically modified organisms (GMO), reference materials, cell lines, CSF, body fluids) from individuals participating in clinical research projects primarily with HIV, viral hepatitis or a range other emerging infectious diseases (influenza, tuberculosis, sexually transmissible infections) of public health importance.
A significant feature of the AMR biorepository is careful management of many of the issues around ethics and compliance that pertain to the use of human blood and tissues in medical research. We seek to harmonise, wherever possible, technical procedures, material transfer agreements and consent forms between all parties involved to streamline administrative ‘red tape’ which can impede productive collaboration between contributors and collaborating researchers.
Contributions to the BioBank are received through a growing number of investigators through a variety of established and recognised networks across multiple sites often associated with large scale multicentre and international observational, epidemiological and clinical research studies.
The St Vincents Biobank services are available on a cost recovery basis and managed under a negotiated Service Agreement contract.
The St Vincent’s Biorepository provides St Vincent’s Hospital Darlinghurst researchers with infrastructure to help coordinate and facilitate collection, processing and storage of human biospecimens for use in biomedical research and clinical trials.
Biorepository Brochure (PDF)